COVID-19 and influenza vaccine uptake among pregnant women in national cohorts of England and Wales

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Gu, Xinchun and Agrawal, Utkarsh and Midgley, William and Bedston, Stuart and Anand, Sneha N. and Goudie, Rosalind and Byford, Rachel and Joy, Mark and Jamie, Gavin and Hoang, Uy and Ordóñez-Mena, Jose M. and Robertson, Chris and Hobbs, F. D. Richard and Akbari, Ashley and Sheikh, Aziz and de Lusignan, Simon (2024) COVID-19 and influenza vaccine uptake among pregnant women in national cohorts of England and Wales. npj Vaccines, 9. 147. ISSN 2059-0105 (https://doi.org/10.1038/s41541-024-00934-9)

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Abstract

Vaccines against COVID-19 and influenza can reduce the adverse outcomes caused by infections during pregnancy, but vaccine uptake among pregnant women has been suboptimal. We examined the COVID-19 and influenza vaccine uptake and disparities in pregnant women during the COVID-19 pandemic to inform vaccination interventions. We used data from the Oxford-Royal College of General Practitioners Research and Surveillance Centre database in England and the Secure Anonymised Information Linkage Databank in Wales. The uptake of at least one dose of vaccine was 40.2% for COVID-19 and 41.8% for influenza among eligible pregnant women. We observed disparities in COVID-19 and influenza vaccine uptake, with socioeconomically deprived and ethnic minority groups showing lower vaccination rates. The suboptimal uptake of COVID-19 and influenza vaccines, especially in those from socioeconomically deprived backgrounds and Black, mixed or other ethnic groups, underscores the necessity for interventions to reduce vaccine hesitancy and enhance acceptance in pregnant women.

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