Integrated filtration and washing modelling : optimization of impurity rejection for the filtration and washing of active pharmaceutical ingredients

Ottoboni, Sara and Mehta, Bhavik and Gramadnikova, Ekaterina and Brown, Cameron J. and Mitchell, Niall A. (2022) Integrated filtration and washing modelling : optimization of impurity rejection for the filtration and washing of active pharmaceutical ingredients. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

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Abstract

Context: Transitioning pharmaceutical manufacturing from batch to continuous provides opportunity to improve sustainability. Aim: Develop an integrated mechanistic filtration and washing model and accompanying optimization workflow to minimize impurities in the isolated filter cake.

ORCID iDs

Ottoboni, Sara ORCID logoORCID: https://orcid.org/0000-0002-2792-3011, Mehta, Bhavik, Gramadnikova, Ekaterina, Brown, Cameron J. ORCID logoORCID: https://orcid.org/0000-0001-7091-1721 and Mitchell, Niall A.;

Persistent Identifier

https://doi.org/10.17868/strath.00081271
CORE (COnnecting REpositories)