Surface enhanced Raman scattering for the multiplexed detection of pathogenic microorganisms : towards point-of-use applications

Berry, Matthew E. and Kearns, Hayleigh and Graham, Duncan and Faulds, Karen (2021) Surface enhanced Raman scattering for the multiplexed detection of pathogenic microorganisms : towards point-of-use applications. Analyst, 146 (20). pp. 6084-6101. ISSN 0003-2654 (https://doi.org/10.1039/D1AN00865J)

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Abstract

Surface enhanced Raman scattering (SERS) is a technique that demonstrates a number of advantages for the rapid, specific and sensitive detection of pathogenic microorganisms. In this review, an overview of label-free and label-based SERS approaches, including microfluidics, nucleic acid detection and immunoassays, for the multiplexed detection of pathogenic bacteria and viruses from the last decade will be discussed, as well as the progress made within the field towards the development of promising point-of-use detection technologies in industrial and medicals settings.