Advances in the cobalt-catalysed Pauson-Khand reaction : development of a sulfide-promoted, microwave-assisted protocol

Cochrane, Alison R. and Kerr, William J. and Paterson, Laura C. and Pearson, Colin M. and Shaw, Paul (2021) Advances in the cobalt-catalysed Pauson-Khand reaction : development of a sulfide-promoted, microwave-assisted protocol. Tetrahedron, 78. 131805. ISSN 0040-4020 (https://doi.org/10.1016/j.tet.2020.131805)

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Abstract

The development of a sulfide-promoted, microwave-assisted Pauson-Khand reaction has enabled the formation of fused cyclopentenones using sub-stoichiometric quantities of a cobalt mediator over rapid reaction times and with no requirement for an external source of toxic carbon monoxide gas. This protocol displays applicability to both intra- and intermolecular Pauson-Khand reaction examples.

ORCID iDs

Cochrane, Alison R., Kerr, William J. ORCID logoORCID: https://orcid.org/0000-0002-1332-785X, Paterson, Laura C., Pearson, Colin M. and Shaw, Paul;
CORE (COnnecting REpositories)