XRT : Extraction of quantitative structural descriptors from solid pharmaceutical products

Doerr, Frederik J. S. and Florence, Alastair J. (2018) XRT : Extraction of quantitative structural descriptors from solid pharmaceutical products. In: Bruker Micro-CT User Meeting, 2018-04-16 - 2018-04-19.

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Abstract

In this project we demonstrate the use of x-ray tomography for the quantification of structural descriptors from two selected solid pharmaceutical products: single formulated particles and a commercial Ibuprofen capsule. In particular, we demonstrate the application of image processing strategies for noise reduction, image segmentation and the extraction of quantitative structural descriptors. Information on the sample’s solid state properties can be used to evaluate the manufacturing process and allows a prediction of the solid performance for subsequent processing steps or after administration to the patient.

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Item metadata

Item type:	Conference or Workshop Item(Speech)
ID code:	73803
Dates:	Date Event 17 April 2018 Published
Subjects:	Medicine > Therapeutics. Pharmacology
Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences Strategic Research Themes > Advanced Manufacturing and Materials Technology and Innovation Centre > Continuous Manufacturing and Crystallisation (CMAC)
Depositing user:	Pure Administrator
Date deposited:	15 Sep 2020 08:32
Last modified:	09 Apr 2024 06:45
URI:	https://strathprints.strath.ac.uk/id/eprint/73803

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