Multiplex in vitro detection using SERS

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Laing, Stacey and Gracie, Kirsten and Faulds, Karen (2016) Multiplex in vitro detection using SERS. Chemical Society Reviews, 45 (7). pp. 1901-1918. ISSN 0306-0012 (https://doi.org/10.1039/c5cs00644a)

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Abstract

The ability to detect multiple disease-related targets from a single biological sample in a quick and reliable manner is of high importance in diagnosing and monitoring disease. The technique known as surface enhanced Raman scattering (SERS) has been developed for the simultaneous detection of multiple targets present in biological samples. Advances in the SERS method have allowed for the sensitive and specific detection of biologically relevant targets, such as DNA and proteins, which could be useful for the detection and control of disease. This review focuses on the strengths of SERS for the detection of target molecules from complex mixtures and the clinical relevance of recent work combining SERS with multiplexed detection of biological targets.

ORCID iDs

Laing, Stacey ORCID logoORCID: https://orcid.org/0000-0001-5781-349X, Gracie, Kirsten ORCID logoORCID: https://orcid.org/0000-0003-3149-3357 and Faulds, Karen ORCID logoORCID: https://orcid.org/0000-0002-5567-7399;
CORE (COnnecting REpositories)