Preparation of [3H]fluoroethyl tosylate and its use in the labelling of the dopamine transporter radioligand [3H]FE-PE2I

Cochrane, Alison Ruth and Kerr, William and Sandell, Johan (2013) Preparation of [3H]fluoroethyl tosylate and its use in the labelling of the dopamine transporter radioligand [3H]FE-PE2I. Journal of Labelled Compounds and Radiopharmaceuticals, 56 (9-10). pp. 447-450. ISSN 0362-4803 (https://doi.org/10.1002/jlcr.3012)

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Abstract

[3H]Fluoroethyl tosylate, a novel alkylating tritium labelling agent, was synthesized from tritium gas with high specific activity and with 99% radiochemical purity. [3H]Fluoroethyl tosylate was applied in the tritium labelling of the dopamine transporter radioligand [3H]FE-PE2I.