Enzyme-responsive polymer hydrogel particles for controlled release

Thornton, Paul D. and Mart, Robert J. and Ulijn, Rein V. (2007) Enzyme-responsive polymer hydrogel particles for controlled release. Advanced Materials, 19 (9). pp. 1252-1256. ISSN 0935-9648 (https://doi.org/10.1002/adma.200601784)

Abstract

A conceptually new approach to polymer-based enzyme-triggered release is described, whereby the selective catalytic action of (disease-specific) enzymes triggers a charge-induced swelling response in chemically crosslinked hydrogel particles, resulting in the release of physically entrapped macromolecules (see figure).

ORCID iDs

Ulijn, Rein V. ORCID: https://orcid.org/0000-0001-7974-3779

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• Item metadata

  Item type:	Article
  ID code:	43950
  Dates:	Date Event 7 May 2007 Published
  Subjects:	Science > Chemistry
  Department:	Faculty of Science > Pure and Applied Chemistry
  Depositing user:	Pure Administrator
  Date deposited:	30 May 2013 11:56
  Last modified:	31 Jan 2025 18:55
  URI:	https://strathprints.strath.ac.uk/id/eprint/43950