Evaluation of alternative solvents in common amide coupling reactions : replacement of dichloromethane and N,N-dimethylformamide

MacMillan, Donna and Murray, J and Sneddon, Helen F. and Jamieson, Craig and Watson, Allan (2013) Evaluation of alternative solvents in common amide coupling reactions : replacement of dichloromethane and N,N-dimethylformamide. Green Chemistry, 15 (3). pp. 596-600. ISSN 1463-9262 (https://doi.org/10.1039/c2gc36900a)

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Abstract

A range of alternative solvents have been evaluated within amidation reactions employing common coupling reagents with a view to identifying suitable replacements for dichloromethane and N,N-dimethylformamide