Z-selective dimerization of aromatic terminal alkynes catalyzed by an iridium(I) n-heterocyclic carbene-phosphine system

Forsyth, Calum and Kerr, William J and Paterson, Laura (2013) Z-selective dimerization of aromatic terminal alkynes catalyzed by an iridium(I) n-heterocyclic carbene-phosphine system. Synlett, 24 (5). pp. 587-590. ISSN 0936-5214 (https://doi.org/10.1055/s-0032-1318271)

[thumbnail of Kerr_Ir_Cat_Alkyne_Dimerization_Synlett_Published.pdf]
Preview
 PDF. Filename: Kerr_Ir_Cat_Alkyne_Dimerization_Synlett_Published.pdf
Final Published Version
Download (211kB)| Preview

Abstract

The development of an iridium-catalyzed regio- and stereoselective dimerization process has enabled the formation of (Z)-enyne products. More specifically, low catalyst loadings of an iridium(I) complex, featuring a bulky N-heterocyclic carbene-phosphine ligand combination, has been successfully employed in this selective head-to-head dimerization of terminal alkynes via C-H activation.

ORCID iDs

Forsyth, Calum, Kerr, William J ORCID logoORCID: https://orcid.org/0000-0002-1332-785X and Paterson, Laura;
CORE (COnnecting REpositories)