A simple and versatile method to determine the enantiomeric purity of Diels-Alder adducts

Hall, Adrian and Harris, Lisa D. and Jones, Claire L. and Jenkins, Robert L. and Tomkinson, Nicholas C. O. (2003) A simple and versatile method to determine the enantiomeric purity of Diels-Alder adducts. Tetrahedron Letters, 44 (1). pp. 111-114. ISSN 0040-4039 (https://doi.org/10.1016/S0040-4039(02)02454-1)

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Abstract

The detn. of the enantiomeric purity of Diels-Alder adducts derived from cyclopentadiene and electron-deficient dienophiles is conveniently achieved by HPLC anal. on their 2,4-dinitrophenylhydrazine derivs. formed in one pot directly from the cycloaddn. reaction.

ORCID iDs

Hall, Adrian, Harris, Lisa D., Jones, Claire L., Jenkins, Robert L. and Tomkinson, Nicholas C. O. ORCID logoORCID: https://orcid.org/0000-0002-5509-0133;