Organocatalytic α-oxybenzoylation of aldehydes

Vaismaa, Matti J. P. and Yau, Sze Chak and Tomkinson, Nicholas C. O. (2009) Organocatalytic α-oxybenzoylation of aldehydes. Tetrahedron Letters, 50 (26). pp. 3625-3627. ISSN 0040-4039 (https://doi.org/10.1016/j.tetlet.2009.03.082)

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Abstract

A simple method for the asymmetric α-oxybenzoylation of aldehydes is presented. Treatment of a series of aldehydes with benzoyl peroxide in the presence of a MacMillan imidazolidinone leads directly to the α-oxybenzoylated product with excellent levels of asymmetric induction.

ORCID iDs

Vaismaa, Matti J. P., Yau, Sze Chak and Tomkinson, Nicholas C. O. ORCID logoORCID: https://orcid.org/0000-0002-5509-0133;