Effects of substituting Fructose by Mannitol in a pharmaceutical formulation

Schmidt, E. and Ford, S. and Dooley, N. and Elliot, M. and Halbert, G. (2010) Effects of substituting Fructose by Mannitol in a pharmaceutical formulation. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1428-1429. ISSN 0022-3573 (https://doi.org/10.1111/j.2042-7158.2010.01178.x)

Abstract

Pharmaceutical formulations can increase the solubility and stability of drug molecules. L-p-10 Boronphenylalanine (BPA) has previously been formulated with Fructose. Here we present a novel BPA formulation with Mannitol resulting in improved kinetic solubility along with the removal of possible Fructose related intolerance reactions.

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• Item metadata

  Item type:	Article
  ID code:	31392
  Dates:	Date Event October 2010 Published 3 September 2010 Published Online
  Subjects:	Medicine > Pharmacy and materia medica
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Pure Administrator
  Date deposited:	24 Jun 2011 10:48
  Last modified:	08 Apr 2024 19:09
  URI:	https://strathprints.strath.ac.uk/id/eprint/31392