Microarray methods for protein biomarker detection

Lee, H.J. and Wark, A.W. and Corn, R.M. (2008) Microarray methods for protein biomarker detection. Analyst, 133 (8). pp. 975-983. ISSN 0003-2654 (http://dx.doi.org/10.1039/b717527b)

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Abstract

The application of protein biomarkers as an aid for the detection and treatment of diseases has been subject to intensified interest in recent years. The quantitative assaying of protein biomarkers in easily obtainable biological fluids such as serum and urine offers the opportunity to improve patient care via earlier and more accurate diagnoses in a convenient, non-invasive manner as well as providing a potential route towards more individually targeted treatment. Essential to achieving progress in biomarker technology is the ability to screen large numbers of proteins simultaneously in a single experiment with high sensitivity and selectivity. In this article, we highlight recent progress in the use of microarrays for high-throughput biomarker profiling and discuss some of the challenges associated with these efforts.

  • Item type:Article
    ID code:19588
    Dates:
    Date
    Event
    2008
    Published
    Notes:This article was featured on the front coverpage with artwork provided by the authors.
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Strathprints Administrator
    Date deposited:02 Jun 2010 10:14
    Last modified:08 Apr 2024 17:33
    URI:https://strathprints.strath.ac.uk/id/eprint/19588
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