Integrated filtration and washing modelling : optimization of impurity rejection for the filtration and washing of active pharmaceutical ingredients

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Ottoboni, Sara and Mehta, Bhavik and Gramadnikova, Ekaterina and Brown, Cameron J. and Mitchell, Niall A. (2022) Integrated filtration and washing modelling : optimization of impurity rejection for the filtration and washing of active pharmaceutical ingredients. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

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Abstract

Context: Transitioning pharmaceutical manufacturing from batch to continuous provides opportunity to improve sustainability. Aim: Develop an integrated mechanistic filtration and washing model and accompanying optimization workflow to minimize impurities in the isolated filter cake.

ORCID iDs

Ottoboni, Sara ORCID logoORCID: https://orcid.org/0000-0002-2792-3011, Mehta, Bhavik, Gramadnikova, Ekaterina, Brown, Cameron J. ORCID logoORCID: https://orcid.org/0000-0001-7091-1721 and Mitchell, Niall A.;
CORE (COnnecting REpositories)