XRT : Extraction of quantitative structural descriptors from solid pharmaceutical products
Doerr, Frederik J. S. and Florence, Alastair J. (2018) XRT : Extraction of quantitative structural descriptors from solid pharmaceutical products. In: Bruker Micro-CT User Meeting, 2018-04-16 - 2018-04-19.
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Abstract
In this project we demonstrate the use of x-ray tomography for the quantification of structural descriptors from two selected solid pharmaceutical products: single formulated particles and a commercial Ibuprofen capsule. In particular, we demonstrate the application of image processing strategies for noise reduction, image segmentation and the extraction of quantitative structural descriptors. Information on the sample’s solid state properties can be used to evaluate the manufacturing process and allows a prediction of the solid performance for subsequent processing steps or after administration to the patient.
ORCID iDs
Doerr, Frederik J. S. ORCID: https://orcid.org/0000-0001-5245-0503 and Florence, Alastair J. ORCID: https://orcid.org/0000-0002-9706-8364;-
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Item type: Conference or Workshop Item(Speech) ID code: 73803 Dates: DateEvent17 April 2018PublishedSubjects: Medicine > Therapeutics. Pharmacology Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Strategic Research Themes > Advanced Manufacturing and Materials
Technology and Innovation Centre > Continuous Manufacturing and Crystallisation (CMAC)Depositing user: Pure Administrator Date deposited: 15 Sep 2020 08:32 Last modified: 12 Dec 2024 16:32 URI: https://strathprints.strath.ac.uk/id/eprint/73803