A traceless solid-phase synthesis of pteridines

Gibson, C.L. and La Rosa, S. and Suckling, C.J. (2003) A traceless solid-phase synthesis of pteridines. Tetrahedron Letters, 44 (6). pp. 1267-1270. ISSN 0040-4039 (https://doi.org/10.1016/S0040-4039(02)02782-X)

Abstract

The linking of pyrimidines to polystyrene supports via either a 2- or 4-thioether provides access to pteridines through solid-phase synthesis. Oxidative cleavage (dimethyldioxirane) followed by nucleophilic substitution by amines, azide, or water completes a traceless synthesis of pteridines.

ORCID iDs

Gibson, C.L. ORCID: https://orcid.org/0000-0003-4948-1266

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• Item metadata

  Item type:	Article
  ID code:	723
  Dates:	Date Event 3 February 2003 Published
  Subjects:	Science > Chemistry
  Department:	Faculty of Science > Pure and Applied Chemistry Unknown Department
  Depositing user:	Users 41 not found.
  Date deposited:	05 Apr 2006
  Last modified:	11 Nov 2024 08:24
  URI:	https://strathprints.strath.ac.uk/id/eprint/723