Picture of boy being examining by doctor at a tuberculosis sanatorium

Understanding our future through Open Access research about our past...

Strathprints makes available scholarly Open Access content by researchers in the Centre for the Social History of Health & Healthcare (CSHHH), based within the School of Humanities, and considered Scotland's leading centre for the history of health and medicine.

Research at CSHHH explores the modern world since 1800 in locations as diverse as the UK, Asia, Africa, North America, and Europe. Areas of specialism include contraception and sexuality; family health and medical services; occupational health and medicine; disability; the history of psychiatry; conflict and warfare; and, drugs, pharmaceuticals and intoxicants.

Explore the Open Access research of the Centre for the Social History of Health and Healthcare. Or explore all of Strathclyde's Open Access research...

Image: Heart of England NHS Foundation Trust. Wellcome Collection - CC-BY.

Strathprints

Advances in biofunctional SERS-active nanoparticles for future clinical diagnostics and therapeutics

Asiala, Steven and Barrett, Lee and Mabbott, Samuel and Graham, Duncan (2016) Advances in biofunctional SERS-active nanoparticles for future clinical diagnostics and therapeutics. In: Frontiers of Plasmon Enhanced Spectroscopy. ACS Symposium Series, 1 . American Chemical Society, Washington, DC, pp. 131-161. ISBN 9780841232013

Full text not available in this repository. Request a copy from the Strathclyde author

Abstract

The synergy afforded by the combination of biofunctionalised nanoparticles and surface enhanced Raman scattering (SERS) has expanded the analytical toolbox for clinical diagnostics and therapeutics. Since their inception, SERS-active nanoparticles have been developed into biofunctional nanoparticles (BFNPs) using a variety of methods to attach biomolecules and pacification layers to nanoparticles to enable detection of various diseases or cancers in vitro and in vivo. However, while there are many reports of the use of BFNPs for diagnostic or therapeutic applications, very few are implemented in a “real” clinical setting, for example, detection of disease biomarkers in tissue or the delivery of drugs to affected cells. This review covers recent advances made in the development of BFNPs for SERS-based detection of clinical samples using in vitro and in vivo methods.

Item type: Book Section
ID code: 60405
Keywords: nanoparticles, biofunctionalised, synergy, surface enhanced Raman scattering, biofunctional nanoparticles, SERS-based detection, in-vitro, in-vivo, clinical diagnostics, therapeutics, Chemistry, Chemistry(all)
Subjects: Science > Chemistry
Department: Faculty of Science > Pure and Applied Chemistry
Technology and Innovation Centre > Bionanotechnology
Depositing user: Pure Administrator
Date deposited: 05 Apr 2017 11:45
Last modified: 30 Jan 2019 16:54
URI: https://strathprints.strath.ac.uk/id/eprint/60405
Export data:
CORE (COnnecting REpositories)