New avenues for drug delivery in Leishmania : using treatment of visceral leishmaniasis with amphotericin B as an exemplar

Carter, Katharine C. and Mullen, Alexander B.; Rivas, Luis and Gil, Carmen, eds. (2017) New avenues for drug delivery in Leishmania : using treatment of visceral leishmaniasis with amphotericin B as an exemplar. In: Drug Discovery in Leishmaniasis. Royal Society of Chemistry, Croydon, 224 - 234. ISBN 9781788012584

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Abstract

In this review the benefits of using a drug delivery system (DDS) to improve therapeutic outcome will be discussed using treatment of visceral leishmaniasis with amphotericin B (AMB), a poorly water soluble drug, as an exemplar. Progress in producing AMB formulations that can be given by intravenous, oral and pulmonary routes of administration is discussed.

ORCID iDs

Carter, Katharine C. and Mullen, Alexander B. ORCID logoORCID: https://orcid.org/0000-0001-7475-5543; Rivas, Luis and Gil, Carmen