Picture of blood cells

Open Access research which pushes advances in bionanotechnology

Strathprints makes available scholarly Open Access content by researchers in the Strathclyde Institute of Pharmacy & Biomedical Sciences (SIPBS) , based within the Faculty of Science.

SIPBS is a major research centre in Scotland focusing on 'new medicines', 'better medicines' and 'better use of medicines'. This includes the exploration of nanoparticles and nanomedicines within the wider research agenda of bionanotechnology, in which the tools of nanotechnology are applied to solve biological problems. At SIPBS multidisciplinary approaches are also pursued to improve bioscience understanding of novel therapeutic targets with the aim of developing therapeutic interventions and the investigation, development and manufacture of drug substances and products.

Explore the Open Access research of SIPBS. Or explore all of Strathclyde's Open Access research...

Wave loading fatigue reliability and uncertainty analyses for geotechnical pipeline models

Elosta, Hany and Huang, Shan and Incecik, Atilla (2014) Wave loading fatigue reliability and uncertainty analyses for geotechnical pipeline models. Ships and Offshore Structures, 9 (4). pp. 450-463. ISSN 1754-212X

Full text not available in this repository.Request a copy from the Strathclyde author


The challenges involved with the fatigue damage assessment of a catenary pipeline in the touchdown zone (TDZ) are primarily because of the non-linear behaviour of pipe-seabed interaction and considerable uncertainty in geotechnical model parameters. The research undertaken in this study investigates the sensitivity of fatigue performance to geotechnical parameters through a parametric study. Furthermore, this paper presents the probability of failure associated with fatigue analysis of a catenary pipeline in the TDZ due to the uncertainty in seabed response model and geotechnical parameters. A first-order reliability method is used for predicting the fatigue safety index. The fatigue analysis results prove that the confounding results indicated by the previous research studies on the catenary pipeline in the TDZ are due to different geotechnical parameters imposed with the soil model. The main benefit of employing a reliability-based fatigue analysis framework is that it enhances the confidence in the steel catenary riser analysis with seabed interaction.