Molar efficiency : a useful metric to gauge relative reaction efficiency in discovery medicinal chemistry

McGonagle, Fiona I. and Sneddon, Helen F. and Jamieson, Craig and Watson, Allan (2014) Molar efficiency : a useful metric to gauge relative reaction efficiency in discovery medicinal chemistry. ACS Sustainable Chemistry and Engineering, 2 (3). pp. 523-532. ISSN 2168-0485 (https://doi.org/10.1021/sc4004532)

Abstract

The concept of molar efficiency is introduced as a new metric to enable assessment of reaction efficiency in discovery medicinal chemistry. Calculations from molar units enable cross-comparison of the broad range of transformations employed in discovery-phase medicinal chemistry research and is proposed to facilitate identification of more sustainable synthetic transformations.

ORCID iDs

Jamieson, Craig ORCID: https://orcid.org/0000-0002-6567-8272

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• Item metadata

  Item type:	Article
  ID code:	48032
  Dates:	Date Event 3 March 2014 Published
  Subjects:	Science > Chemistry
  Department:	Faculty of Science > Pure and Applied Chemistry
  Depositing user:	Pure Administrator
  Date deposited:	13 May 2014 09:03
  Last modified:	01 Dec 2024 22:49
  Related URLs:	Scopus publication
  URI:	https://strathprints.strath.ac.uk/id/eprint/48032