Aminocatalytic preparation of bisindolylalkanes

Gibbs, Timothy J. K. and Tomkinson, Nicholas C. O. (2005) Aminocatalytic preparation of bisindolylalkanes. Organic and Biomolecular Chemistry, 3 (22). pp. 4043-4045. ISSN 1477-0520 (https://doi.org/10.1039/b513394g)

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Abstract

An aminocatalytic method for the formation of bisindolylalkanes, e.g. I (R = Et, cyclopropyl, Ph) is described; the reaction proceeds effectively at ambient temp. in the presence of moisture and air for both aldehyde and ketone substrates and has been applied to the one-step prepn. of a series of naturally-occurring bis- and tris-indolylalkanes.

ORCID iDs

Gibbs, Timothy J. K. and Tomkinson, Nicholas C. O. ORCID logoORCID: https://orcid.org/0000-0002-5509-0133;