Inflammatory response to orthopaedic cobalt chromium alloy wear debris in a rodent air pouch model

Akbar, M. and Brewer, J.M. and Grant, M.H. (2010) Inflammatory response to orthopaedic cobalt chromium alloy wear debris in a rodent air pouch model. Toxicology Letters, 196S. S199. ISSN 0378-4274 (https://doi.org/10.1016/j.toxlet.2010.03.675)

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Abstract

Cobalt chromium (Co-Cr) alloy metal-on-metal (MOM) hip resurfacing has become increasingly common in younger, more active patients. However, there is growing concern regarding levels of Co-Cr wear debris and ions released. Using the rodent air pouch model, described as a facsimile synovium, we assessed the inflammatory response to artificially generated Co-Cr wear debris.

ORCID iDs

Akbar, M., Brewer, J.M. and Grant, M.H. ORCID logoORCID: https://orcid.org/0000-0002-7712-404X;
CORE (COnnecting REpositories)