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SERRS as a more sensitive technique for the detection of labelled oligonucleotides compared to fluorescence

Faulds, K. and Barbagallo, R.P. and Keer, J.T. and Smith, W.E. and Graham, D. (2004) SERRS as a more sensitive technique for the detection of labelled oligonucleotides compared to fluorescence. Analyst, 129 (7). pp. 567-568. ISSN 0003-2654

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Abstract

This communication contains data from a comparison between the detection limits obtained using surface enhanced resonance Raman scattering (SERRS) and fluorescence detection of dye labelled oligonucleotides. The results show that the detection limits for SERRS are generally at least three orders of magnitude lower than those obtained for fluorescence.