Synthesis of a benzotriazole azo dye phosphoramidite for labelling of oligonucleotides

Brown, R. and Smith, W.E. and Graham, D. (2003) Synthesis of a benzotriazole azo dye phosphoramidite for labelling of oligonucleotides. Tetrahedron Letters, 44 (7). pp. 1339-1342. ISSN 0040-4039 (http://dx.doi.org/10.1016/S0040-4039(02)02886-1)

Abstract

The synthesis of a benzotriazole azo dye phosphoramidite and the subsequent use in solid phase synthesis of oligonucleotides is reported. The azo dye is shown as a surface enhanced resonance Raman label for oligonucleotides that is capable of immobilisation of the oligonucleotide on metal surfaces such as silver nanoparticles. (C) 2003 Elsevier Science Ltd. All rights reserved.

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• Item metadata

  Item type:	Article
  ID code:	1099
  Dates:	Date Event 10 February 2003 Published
  Subjects:	Science > Chemistry
  Department:	Faculty of Science > Pure and Applied Chemistry Unknown Department
  Depositing user:	Mr Derek Boyle
  Date deposited:	18 May 2006
  Last modified:	08 Apr 2024 15:27
  Related URLs:	http://www.sciencedirect.com/science?_ob...
  URI:	https://strathprints.strath.ac.uk/id/eprint/1099