Biofabrication and biomanufacturing in Ireland and the UK

Murphy, Jack F. and Lavelle, Martha and Asciak, Lisa and Burdis, Ross and Levis, Hannah J. and Ligorio, Cosimo and McGuire, Jamie and Polleres, Marlene and Smith, Poppy O. and Tullie, Lucinda and Uribe-Gomez, Juan and Chen, Biqiong and Dawson, Jonathan I. and Gautrot, Julien E. and Hooper, Nigel M. and Kelly, Daniel J. and Li, Vivian S. W. and Mata, Alvaro and Pandit, Abhay and Phillips, James B. and Shu, Wenmiao and Stevens, Molly M. and Williams, Rachel L. and Armstrong, James P. K. and Huang, Yan Yan Shery (2024) Biofabrication and biomanufacturing in Ireland and the UK. Bio-Design and Manufacturing, 7 (6). pp. 825-856. ISSN 2096-5524 (https://doi.org/10.1007/s42242-024-00316-z)

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Abstract

As we navigate the transition from the Fourth to the Fifth Industrial Revolution, the emerging fields of biomanufacturing and biofabrication are transforming life sciences and healthcare. These sectors are benefiting from a synergy of synthetic and engineering biology, sustainable manufacturing, and integrated design principles. Advanced techniques such as 3D bioprinting, tissue engineering, directed assembly, and self-assembly are instrumental in creating biomimetic scaffolds, tissues, organoids, medical devices, and biohybrid systems. The field of biofabrication in the United Kingdom and Ireland is emerging as a pivotal force in bioscience and healthcare, propelled by cutting-edge research and development. Concentrating on the production of biologically functional products for use in drug delivery, in vitro models, and tissue engineering, research institutions across these regions are dedicated to innovating healthcare solutions that adhere to ethical standards while prioritising sustainability, affordability, and healthcare system benefits.

ORCID iDs

Murphy, Jack F., Lavelle, Martha, Asciak, Lisa ORCID logoORCID: https://orcid.org/0009-0008-8285-198X, Burdis, Ross, Levis, Hannah J., Ligorio, Cosimo, McGuire, Jamie, Polleres, Marlene, Smith, Poppy O., Tullie, Lucinda, Uribe-Gomez, Juan, Chen, Biqiong, Dawson, Jonathan I., Gautrot, Julien E., Hooper, Nigel M., Kelly, Daniel J., Li, Vivian S. W., Mata, Alvaro, Pandit, Abhay, Phillips, James B., Shu, Wenmiao ORCID logoORCID: https://orcid.org/0000-0002-1220-361X, Stevens, Molly M., Williams, Rachel L., Armstrong, James P. K. and Huang, Yan Yan Shery;