Drug utilization research in the area of cancer drugs

Mueller, Tanja and Hoffmann, Mikael; Elseviers, Monique and Wettermark, Björn and Benkő, Ria and Bennie, Marion and Gvozdanović, Katarina and Hoffmann, Mikael and Iaru, Irina and Ivanovska, Verica and MacBride-Stewart, Sean and Mueller, Tanja and Poluzzi, Elisabetta and Pont, Lisa and Salvesen Blix, Hege and Sanfélix-Gimeno, Gabriel and Selke, Gisbert and Taxis, Katja and Tomas Petrović, Ana and Trečiokienė, Indrė and Vogler, Sabine, eds. (2024) Drug utilization research in the area of cancer drugs. In: Drug Utilization Research. Wiley-Blackwell, Hoboken, NJ, pp. 373-380. ISBN 9781119911685 (https://doi.org/10.1002/9781119911685.ch36)

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Abstract

The world-wide impact of cancer on life expectancy, quality of life, and need for healthcare interventions together explain the research interest and rapid development of new therapeutic alternatives for the treatment of cancer. This chapter presents the examples for the main types of systemic anti-cancer therapy (SACT) currently in use. In Europe most cancer drugs are authorised by the European Medicines Agency through centralised marketing authorisation applications. Studying utilization of cancer drugs introduces additional and severe challenges compared to many other therapeutic areas. The concept of defined daily doses needs to be handled carefully for cancer drugs. Due to the lack of robust ways of measuring the amount of SACT used and the importance placed on the expenditures on cancer drugs, international comparisons in particular tend to focus on total cost of the drugs instead of amount distributed.

ORCID iDs

Mueller, Tanja ORCID logoORCID: https://orcid.org/0000-0002-0418-4789 and Hoffmann, Mikael; Elseviers, Monique, Wettermark, Björn, Benkő, Ria, Bennie, Marion, Gvozdanović, Katarina, Hoffmann, Mikael, Iaru, Irina, Ivanovska, Verica, MacBride-Stewart, Sean, Mueller, Tanja, Poluzzi, Elisabetta, Pont, Lisa, Salvesen Blix, Hege, Sanfélix-Gimeno, Gabriel, Selke, Gisbert, Taxis, Katja, Tomas Petrović, Ana, Trečiokienė, Indrė and Vogler, Sabine
CORE (COnnecting REpositories)