Quantification of RNA degradation of blood-specific markers to indicate age of bloodstains

Alshehhi, Suaad and Haddrill, Penny; (2018) Quantification of RNA degradation of blood-specific markers to indicate age of bloodstains. In: Scottish Institute for Policing Research Annual Report 2017/18. The Scottish Institute for Policing Research, Edinburgh, pp. 46-47. (http://www.sipr.ac.uk/Plugin/Publications/assets/f...)

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Abstract

Recently, there has been increasing interest in the use of Ribonucleic Acid (RNA) in the forensic science community, for various applications. Some RNA types such as messenger RNA (mRNA) and microRNA (miRNA) have shown the ability to reveal the activities of genes and their respective cells/tissues, which might help to give an indication of pathological states or any condition that leads to death. These molecules have also proved to be potential tools to identify the origin of a body fluid and give some indication of the time it was deposited. Since 1983, when RNA first appeared in forensic science, many studies have been carried out to try and understand how patterns of gene expression can be useful in forensic science.

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