An electrochemical SARS-CoV-2 biosensor inspired by glucose test strip manufacturing processes

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Vezza, Vincent J. and Butterworth, Adrian and Lasserre, Perrine and Blair, Ewen O. and MacDonald, Alexander and Hannah, Stuart and Rinaldi, Christopher and Hoskisson, Paul A. and Ward, Andrew C. and Longmuir, Alistair and Setford, Steven and Farmer, Eoghan C. W. and Murphy, Michael E. and Corrigan, Damion K. (2021) An electrochemical SARS-CoV-2 biosensor inspired by glucose test strip manufacturing processes. Chemical Communications, 57 (30). pp. 3704-3707. ISSN 1359-7345 (https://doi.org/10.1039/D1CC00936B)

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Abstract

Accurate and rapid diagnostic tests are critical to reducing the impact of SARS-CoV-2. This study presents early, but promising measurements of SARS-CoV-2 using the ACE2 enzyme as the recognition element to achieve clinically relevant detection. The test provides a scalable route to sensitive, specific, rapid and low cost mass testing.

ORCID iDs

Vezza, Vincent J., Butterworth, Adrian ORCID logoORCID: https://orcid.org/0000-0002-0463-927X, Lasserre, Perrine, Blair, Ewen O. ORCID logoORCID: https://orcid.org/0000-0002-1887-8001, MacDonald, Alexander ORCID logoORCID: https://orcid.org/0000-0003-2252-3147, Hannah, Stuart ORCID logoORCID: https://orcid.org/0000-0001-5620-9899, Rinaldi, Christopher, Hoskisson, Paul A. ORCID logoORCID: https://orcid.org/0000-0003-4332-1640, Ward, Andrew C. ORCID logoORCID: https://orcid.org/0000-0002-5302-5899, Longmuir, Alistair, Setford, Steven, Farmer, Eoghan C. W., Murphy, Michael E. and Corrigan, Damion K. ORCID logoORCID: https://orcid.org/0000-0002-4647-7483;
CORE (COnnecting REpositories)