Temperature profiling of ex-vivo organs during ferromagnetic nanoparticles-enhanced radiofrequency ablation by fiber Bragg grating arrays

Jelbuldina, Madina and Korganbayev, Sanzhar and Korobeinyk, Alina V. and Inglezakis, Vassilis J. and Tosi, Daniele; (2018) Temperature profiling of ex-vivo organs during ferromagnetic nanoparticles-enhanced radiofrequency ablation by fiber Bragg grating arrays. In: 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS . Institute of Electrical and Electronics Engineers Inc., USA. ISBN 9781538636466 (https://doi.org/10.1109/EMBC.2018.8513227)

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Abstract

In this paper, we present real-time profiles of temperature during a ferromagnetic nanoparticles (NPs)enhanced radiofrequency ablation (RFA). A minimally invasive RFA setup has been prepared and applied ex vivo on a liver phantom; NPs (with concentration of 5 mg/mL) have been synthetized and injected within the tissue prior to perform the ablation, in order to facilitate the heat distribution to the peripheral sides of the ablated tissue. Temperature detection has been realized in situ with a network of 15 fiber Bragg grating (FBG) sensors in order to highlight the impact of the NPs on the RFA mechanism. Obtained temperature profiles and thermal maps confirm that nanoparticles injection ensures better heat penetration than in case of pristine RFA procedure. The results show that adding NPs solution leads to extending the successfully ablated area achieving a double-sized lesion.

ORCID iDs

Jelbuldina, Madina, Korganbayev, Sanzhar, Korobeinyk, Alina V., Inglezakis, Vassilis J. ORCID logoORCID: https://orcid.org/0000-0002-0195-0417 and Tosi, Daniele;
  • Item type:Book Section
    ID code:74330
    Dates:
    Date
    Event
    26 October 2018
    Published
    Notes:© 2018 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting /republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
    Subjects:Technology > Chemical engineering
    Department:Faculty of Engineering > Chemical and Process Engineering
    Depositing user: Pure Administrator
    Date deposited:21 Oct 2020 10:09
    Last modified:11 Nov 2024 15:22
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/74330
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