Unexpected nickel complex speciation unlocks alternative pathways for the reactions of alkyl halides with dppf-nickel(0)

Greaves, Megan E. and Ronson, Thomas O. and Lloyd-Jones, Guy C. and Maseras, Feliu and Sproules, Stephen and Nelson, David J. (2020) Unexpected nickel complex speciation unlocks alternative pathways for the reactions of alkyl halides with dppf-nickel(0). ACS Catalysis, 10 (18). pp. 10717-10725. ISSN 2155-5435 (https://doi.org/10.1021/acscatal.0c02514)

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Abstract

The mechanism of the reactions between dppf-Ni0 complexes and alkyl halides has been investigated using kinetic and mechanistic experiments and DFT calculations. The active species is [Ni(κ2-dppf)(κ1-dppf)], which undergoes a halide abstraction reaction with alkyl halides and rapidly captures the alkyl radical that is formed. The rates of the reactions of [Ni(COD)(dppf)] with alkyl halides and the yields of prototypical nickel-catalyzed Kumada cross-coupling reactions of alkyl halides are shown to be significantly improved by the addition of free dppf ligand.

  • Item type:Article
    ID code:73739
    Dates:
    Date
    Event
    18 September 2020
    Published
    21 August 2020
    Published Online
    21 August 2020
    Accepted
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:28 Aug 2020 13:36
    Last modified:22 Apr 2024 03:33
    URI:https://strathprints.strath.ac.uk/id/eprint/73739
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