Stimuli responsive polymeric systems for cancer therapy

Alsuraifi, Ali and Curtis, Anthony and Lamprou, Dimitrios A. and Hoskins, Clare (2018) Stimuli responsive polymeric systems for cancer therapy. Pharmaceutics, 10 (3). pp. 1-17. 136. ISSN 1999-4923 (https://doi.org/10.3390/pharmaceutics10030136)

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Abstract

Nanoscale polymers systems have dominated the revolution of drug delivery advancement. Their potential in the fight against cancer is unrivalled with other technologies. Their functionality increase, targeting ability and stimuli responsive nature have led to a major boom in research focus. This review article concentrates on the use of these smart polymers in cancer therapy. Nanotechnologies have shown potential as drug carriers leading to increased drug efficacy and penetration. Multifunctional smart carriers which can release their payload upon an external or internal trigger such as pH or temperature are proving to be major frontrunners in the development of effective strategies to overcome this disease with minimal patient side effects.

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