Ground state cross-coupling of haloarenes with arenes initiated by organic electron donors, formed in situ : an overview

Nocera, Giuseppe and Murphy, John A. (2019) Ground state cross-coupling of haloarenes with arenes initiated by organic electron donors, formed in situ : an overview. Synthesis, 51. ISSN 0039-7881 (https://doi.org/10.1055/s-0039-1690614)

[thumbnail of Nocera-Murphy-Synthesis-2019-Ground-state-cross-coupling-of-haloarenes-with-arenes]
Preview
 Text. Filename: Nocera_Murphy_Synthesis_2019_Ground_state_cross_coupling_of_haloarenes_with_arenes.pdf
Accepted Author Manuscript
Download (874kB)| Preview

Abstract

Many reactions have been discovered that lead to coupling of haloarenes to arenes using potassium tert-butoxide as the base, and one of a variety of organic compounds as an additive. The organic additive reacts with the base to form a strong organic electron donor in situ that initiates a base-induced homolytic aromatic substitution (BHAS) coupling reaction, by converting the haloarene into an aryl radical. This brief report presents an overview of the wide range of organic additives that can be used, and the organic electron donors that they form.

  • Item type:Article
    ID code:70145
    Dates:
    Date
    Event
    13 September 2019
    Published
    13 September 2019
    Published Online
    5 August 2019
    Accepted
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:16 Oct 2019 15:46
    Last modified:21 Apr 2024 18:06
    URI:https://strathprints.strath.ac.uk/id/eprint/70145
CORE (COnnecting REpositories)