Crystallization and lamellar nanosheet formation of an aromatic dipeptoid

Castelletto, Valeria and Chippindale, Ann M. and Hamley, Ian W. and Barnett, Sarah and Hasan, Abshar and Lau, King Hang Aaron (2019) Crystallization and lamellar nanosheet formation of an aromatic dipeptoid. Chemical Communications, 55 (42). pp. 5867-5869. ISSN 1359-7345 (https://doi.org/10.1039/c9cc02335f)

[thumbnail of Castelletto-etal-CC2019-Crystallization-and-lamellar-nanosheet-formation-of-an-aromatic]
Preview
 Text. Filename: Castelletto_etal_CC2019_Crystallization_and_lamellar_nanosheet_formation_of_an_aromatic.pdf
Accepted Author Manuscript
Download (1MB)| Preview

Abstract

An aromatic peptoid analogue of the diphenylalanine dipeptide self-assembles in aqueous solution and the first crystal structure was obtained for this class of compound. This reveals molecular packing stabilized by networks of hydrogen bonds. Free-floating nanosheet lamellar structures are observed in solution, which form via cooperative intermolecular interactions driven by π stacking.

ORCID iDs

Castelletto, Valeria, Chippindale, Ann M., Hamley, Ian W., Barnett, Sarah, Hasan, Abshar and Lau, King Hang Aaron ORCID logoORCID: https://orcid.org/0000-0003-3676-9228;
CORE (COnnecting REpositories)