Nanomedicines : exploring the past, present and future

Perrie, Yvonne and Ramsay, Euan (2017) Nanomedicines : exploring the past, present and future. Drug Discovery World, 18 (Fall). pp. 17-22. ISSN 1469-4344

[thumbnail of Perrie-Ramsay-DDW-20187-Nanomedicines-exploring-the-past-present]
Preview
 Text. Filename: Perrie_Ramsay_DDW_20187_Nanomedicines_exploring_the_past_present.pdf
Final Published Version
Download (2MB)| Preview

Abstract

Nanoparticles, and liposomes in particular, are growing in popularity as drug delivery vehicles for anti-cancer agents and inflammatory disease therapies, as well as forming the basis of a new class of vaccines. They offer a number of advantages in terms of stability, efficacy and off-target effects, but traditional manufacturing methods are labour-intensive, hard to reproduce and difficult to scale up. This has contributed to a widely-held perception in the pharmaceutical industry that nanomedicines are far from clinically practical. A new generation of microfluidic systems is helping to overcome these issues, allowing the rapid development and seamless scale-up of novel nanoparticles. This technology is transforming the development and manufacture of a range of nanoparticle formulations from a hit-and-miss affair into a standardised process, accelerating novel nanomedicines from the bench to the clinic.

CORE (COnnecting REpositories)