Multi-sensor measurements of quantitative particle size and shape information in crystal slurries

Ferreira, Carla Sofia and Ahmed, Bilal and Cardona, Javier and Agimelen, Okpeafoh and Sefcik, Jan and Chen, Yi-Chieh (2018) Multi-sensor measurements of quantitative particle size and shape information in crystal slurries. In: 8th World Congress on Particle Technology, 2018-04-22 - 2018-04-26, Orlando World Center Marriott.

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Abstract

Particle size and shape are critical quality attributes for active pharmaceutical ingredients (API) as they have direct impact on downstream processing, as well as on the performance behaviour of the finished product. Obtaining a reliable and robust quantitative information of these particle attributes in real-time remains a great challenge across the multiple manufacturing steps and cannot be achieved by just using a single sensor.