Relationship between outdoor temperature and cardiovascular disease risk factors in older people

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Sartini, Claudio and Barry, Sarah J.E. and Whincup, Peter H. and Wannamethee, S. Goya and Lowe, Gordon D.O. and Jefferis, Barbara J. and Lennon, Lucy and Welsh, Paul and Ford, Ian and Sattar, Naveed and Morris, Richard W. (2017) Relationship between outdoor temperature and cardiovascular disease risk factors in older people. European Journal of Preventive Cardiology, 24 (4). pp. 349-356. ISSN 2047-4881 (https://doi.org/10.1177/2047487316682119)

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Abstract

Background: Previous studies demonstrated that lower outdoor temperatures increase the levels of established cardiovascular disease risk factors, such as blood pressure and lipids. Whether or not low temperatures increase novel cardiovascular disease risk factors levels is not well studied. The aim was to investigate associations of outdoor temperature with a comprehensive range of established and novel cardiovascular disease risk factors in two large Northern European studies of older adults, in whom cardiovascular disease risk is increased. Design and methods: Data came from the British Regional Heart Study (4252 men aged 60?79 years) and the Prospective Study of Pravastatin in the Elderly at Risk (5804 men and women aged 70?82 years). Associations between outdoor temperature and cardiovascular disease risk factors were quantified in each study and then pooled using a random effects model. Results: With a 5C lower mean temperature, total cholesterol was 0.04 mmol/l (95% confidence interval (CI) 0.02?0.07) higher, low density lipoprotein cholesterol was 0.02 mmol/l (95% CI 0.01?0.05) higher and SBP was 1.12 mm Hg (95% CI 0.60?1.64) higher. Among novel cardiovascular disease risk factors, C-reactive protein was 3.3% (95% CI 1.0?5.6 higher, interleukin-6 was 2.7% (95% CI 1.1?4.3 higher, and vitamin D was 11.2% (95% CI 1.0?20.4 lower. Conclusions: Lower outdoor temperature was associated with adverse effects on cholesterol, blood pressure, circulating inflammatory markers, and vitamin D in two older populations. Public health approaches to protect the elderly against low temperatures could help in reducing the levels of several cardiovascular disease risk factors.

ORCID iDs

Sartini, Claudio, Barry, Sarah J.E. ORCID logoORCID: https://orcid.org/0000-0003-3039-8729, Whincup, Peter H., Wannamethee, S. Goya, Lowe, Gordon D.O., Jefferis, Barbara J., Lennon, Lucy, Welsh, Paul, Ford, Ian, Sattar, Naveed and Morris, Richard W.;
  • Item type:Article
    ID code:63869
    Dates:
    Date
    Event
    1 March 2017
    Published
    29 November 2016
    Published Online
    10 November 2016
    Accepted
    Notes:This research was supported by a British Heart Foundation (BHF) project grant (PG/13/41/30304) which supported CS. The BRHS is supported by a BHF programme grant (RG/13/16/30528).
    Subjects:Medicine > Medicine (General)
    Department:Faculty of Science > Mathematics and Statistics
    Strategic Research Themes > Health and Wellbeing
    Depositing user: Pure Administrator
    Date deposited:26 Apr 2018 10:28
    Last modified:11 Nov 2024 11:58
    URI:https://strathprints.strath.ac.uk/id/eprint/63869
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