Effect of particle size distribution on spatially and angularly resolved diffuse reflectance measurement

Chen, Yi-Chieh and Tiernan-Vandermotten, Sarra and Lue, Leo and Ferreira, Carla Sofia and Sefcik, Jan and Thennadil, Suresh (2018) Effect of particle size distribution on spatially and angularly resolved diffuse reflectance measurement. European Pharmaceutical Review, 23 (1). pp. 34-37. ISSN 1360-8606

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Abstract

Particle size distribution is vitally important in pharmaceutical formulation. Spectroscopy is the most prominent method for in-line particle measurements and process analytics, and near-infrared (NIR) spectroscopy can be seen as the workhorse in the field of Process Analytical Technology (PAT). This article considers analysis using an innovative spatially and angularly resolved diffuse reflectance measurement (SAR-DRM).

ORCID iDs

Chen, Yi-Chieh ORCID logoORCID: https://orcid.org/0000-0002-8307-0666, Tiernan-Vandermotten, Sarra ORCID logoORCID: https://orcid.org/0000-0002-4962-1495, Lue, Leo ORCID logoORCID: https://orcid.org/0000-0002-4826-5337, Ferreira, Carla Sofia ORCID logoORCID: https://orcid.org/0000-0002-0592-8540, Sefcik, Jan ORCID logoORCID: https://orcid.org/0000-0002-7181-5122 and Thennadil, Suresh;