Cooperative, ion-sensitive co-assembly of tripeptide hydrogels

Abul-Haija, Yousef M. and Scott, Gary G. and Sahoo, Jugal Kishore and Tuttle, Tell and Ulijn, Rein V. (2017) Cooperative, ion-sensitive co-assembly of tripeptide hydrogels. Chemical Communications. pp. 9562-9565. ISSN 1359-7345 (https://doi.org/10.1039/C7CC04796G)

[thumbnail of Abul-Haija-etal-CC-2017-Cooperative-ion-sensitive-coassembly-of-tripeptide-hydrogels]
Preview
 Text. Filename: Abul_Haija_etal_CC_2017_Cooperative_ion_sensitive_coassembly_of_tripeptide_hydrogels.pdf
Final Published Version
License: Creative Commons Attribution 3.0 logo
Download (2MB)| Preview

Abstract

Peptide co-assembly is of interest for the development of functional supramolecular biomaterials. Herein, computational simulations were combined with experimental validation to aid the design and understanding of cooporative co-assembly of a structure-forming tripeptide (FFD) and a functional copper-binding tripeptide (GHK) leading to hydrogel formation in response to complexation with copper ions.

CORE (COnnecting REpositories)