Laser-wakefield accelerators for medical phase contrast imaging : Monte Carlo simulations and experimental studies

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Cipiccia, S. and Reboredo, D. and Vittoria, F. A. and Welsh, G. H. and Grant, P. and Grant, D. W. and Brunetti, E. and Wiggins, S. M. and Olivo, A. and Jaroszynski, D. A.; Ledingham, Kenneth W. D. and Esarey, Eric and Spohr, Klaus and Schroeder, Carl B. and McKenna, Paul and Grüner, Florian J. and Bolton, Paul R., eds. (2015) Laser-wakefield accelerators for medical phase contrast imaging : Monte Carlo simulations and experimental studies. In: Proceedings of SPIE. SPIE--The International Society for Optical Engineering.. ISBN 9781628416350 (https://doi.org/10.1117/12.2178837)

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Abstract

X-ray phase contrast imaging (X-PCi) is a very promising method of dramatically enhancing the contrast of X-ray images of microscopic weakly absorbing objects and soft tissue, which may lead to significant advancement in medical imaging with high-resolution and low-dose. The interest in X-PCi is giving rise to a demand for effective simulation methods. Monte Carlo codes have been proved a valuable tool for studying X-PCi including coherent effects. The laser-plasma wakefield accelerators (LWFA) is a very compact particle accelerator that uses plasma as an accelerating medium. Accelerating gradient in excess of 1 GV/cm can be obtained, which makes them over a thousand times more compact than conventional accelerators. LWFA are also sources of brilliant betatron radiation, which are promising for applications including medical imaging. We present a study that explores the potential of LWFA-based betatron sources for medical X-PCi and investigate its resolution limit using numerical simulations based on the FLUKA Monte Carlo code, and present preliminary experimental results

ORCID iDs

Cipiccia, S., Reboredo, D., Vittoria, F. A., Welsh, G. H. ORCID logoORCID: https://orcid.org/0000-0001-7933-4190, Grant, P. ORCID logoORCID: https://orcid.org/0000-0002-4463-8490, Grant, D. W. ORCID logoORCID: https://orcid.org/0000-0002-1868-2850, Brunetti, E. ORCID logoORCID: https://orcid.org/0000-0001-8302-9762, Wiggins, S. M. ORCID logoORCID: https://orcid.org/0000-0001-7804-6146, Olivo, A. and Jaroszynski, D. A. ORCID logoORCID: https://orcid.org/0000-0002-3006-5492; Ledingham, Kenneth W. D., Esarey, Eric, Spohr, Klaus, Schroeder, Carl B., McKenna, Paul, Grüner, Florian J. and Bolton, Paul R.
  • Item type:Book Section
    ID code:54914
    Dates:
    Date
    Event
    13 April 2015
    Published
    Notes:Copyright 2015 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any materi al in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
    Subjects:Science > Physics
    Department:Faculty of Science > Physics
    Depositing user: Pure Administrator
    Date deposited:11 Dec 2015 04:20
    Last modified:12 Dec 2024 01:09
    URI:https://strathprints.strath.ac.uk/id/eprint/54914
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