The application of micro-plate dynamics on monitoring cell property

Ma, Xianghong and Wu, Zhangming (2008) The application of micro-plate dynamics on monitoring cell property. In: 15th International Conference on Mechatronics and Machine Vision in Practice, M2VIP 2008, 2008-12-02 - 2008-12-04.

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Abstract

The paper presents a novel biosensing method of monitoring cell properties using the information derived from the dynamics of micro-scale plates. Micro cantilevers have been widely applied as mechanical biosensors. In dynamic sense, cantilever is considered as 1 dimensional whereas plate is a 2 dimensional structure. In this paper we provide the first analytical solution to the dynamics of distributed mass loaded microplate in submerged fluid. In a further step, we propose to derive the dynamical infomation of the micro plate and use it to infer the spatial information of the cells when monitoring the cell growth on the plate.

  • Item type:Conference or Workshop Item(Paper)
    ID code:53969
    Dates:
    Date
    Event
    2 December 2008
    Published
    Notes:[1] DR Basel, GU Lee, KM Hansen, LA Chrisey and RJ Colton, "A high-sensitivity micromachined biosensor", Biosensors and Bioelectronics, Volume 12, Issue 8, 1997, Page iv. {2] Fritz, J; Baller, MK; Lang, HP; Rothuizen, H; Vettiger, P; Meyer, E; Güntherodt, H; Gerber, C; Gimzewski, JK, "Translating biomolecular recognition into nanomechanics" Science, Volume 288, Issue 5464, April 14, 2000, Pages 316-318. [3] Passian, A. Muralidharan, G; Mehta, A; Simpson, H; Ferrell, TL; Thundat, T. "Manipulation of microcantilever oscillations", Ultramicroscopy, v 97, n 1-4, October/November, 2003, p 391-399. [4] Lobontiu, Nicolae, Garcia, Ephrahim, "Two microcantilever designs: Lumped-parameter model for static and modal analysis", Journal of Microelectromechanical Systems, v 13, n 1, February, 2004, p 41-50.
    Subjects:Science > Microbiology
    Technology > Mechanical engineering and machinery
    Department:Faculty of Engineering > Mechanical and Aerospace Engineering
    Depositing user: Pure Administrator
    Date deposited:13 Aug 2015 14:47
    Last modified:11 Nov 2024 16:45
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/53969
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