Modern NMR Pulse Sequences in Pharmaceutical R & D

Parkinson, John; Harris, Robin and Everett, Jeremy and Wilson, Ian and Lindon, John, eds. (2015) Modern NMR Pulse Sequences in Pharmaceutical R & D. In: eMagRes. John Wiley & Sons, Ltd., Chichester, UK, pp. 69-82. ISBN 9780470034590 (https://doi.org/10.1002/9780470034590.emrstm1402)

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Abstract

NMR pulse sequences are surveyed for solution-state methods that serve as typical, robust techniques in pharmaceutical or chemical NMR laboratories. Attention is drawn to up-to-date methods capable of enhancing sensitivity, resolution, and information content. Sequences range from those used for pulse calibration and field homogeneity adjustment, through one- and two-dimensional homo- and heteronuclear methods for solution-phase work. Techniques used for editing, resolving, and simplifying data are highlighted and extensive use is made of sequence diagrams to present the basic structure of each pulse sequence in pictorial form. Where appropriate, descriptions of each sequence and some examples of data are provided and attention drawn to the advantages of using each technique.

ORCID iDs

Parkinson, John ORCID logoORCID: https://orcid.org/0000-0003-4270-6135; Harris, Robin, Everett, Jeremy, Wilson, Ian and Lindon, John
CORE (COnnecting REpositories)