New sesquiterpene quinols from a Micronesian sponge, Aka sp

Mukku, Venugopal J R V and Edrada-Ebel, Ruangelie and Schmitz, Francis J and Shanks, Michelle Kelly and Chaudhuri, Babathosh and Fabbro, Doriano (2003) New sesquiterpene quinols from a Micronesian sponge, Aka sp. Journal of Natural Products, 66 (5). pp. 686-689. ISSN 0163-3864 (https://doi.org/10.1021/np0205506)

Abstract

Three new sesquiterpene quinols (1, 2, and 5) and two known ones (3 and 4) were isolated along with halistanol sulfate (6) from a marine sponge of the genus Aka collected from Yap Island, Federated States of Micronesia. Their structures were determined from spectral data, and the structure of siphonodictyal C (3) was revised. Sulfates 3 and 6 inhibit CDK4/cyclin D1 complexation, whereas 1 and 4 do not.

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• Item metadata

  Item type:	Article
  ID code:	48494
  Dates:	Date Event May 2003 Published 25 April 2003 Published Online
  Subjects:	Science > Chemistry Science > Microbiology Medicine > Pharmacy and materia medica
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Pure Administrator
  Date deposited:	11 Jun 2014 13:03
  Last modified:	17 Nov 2024 18:50
  URI:	https://strathprints.strath.ac.uk/id/eprint/48494