Multivalent nanoparticle networks as ultrasensitive enzyme sensors

De La Rica, Roberto and Fratila, Raluca and Szarpak, Anna and Huskens, Jurriaan and Velders, Aldrik (2011) Multivalent nanoparticle networks as ultrasensitive enzyme sensors. Angewandte Chemie International Edition, 50 (25). 5704–5707. ISSN 1521-3773 (https://doi.org/10.1002/anie.201008189)

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Abstract

As few as 23 enzyme molecules could be detected on the basis of the dispersion of Au nanoparticles in a model bioassay whose sensitivity was boosted by the interplay between multivalent and monovalent supramolecular interactions: a diferrocenyl ligand (red) caused the assembly of nanoparticle clusters; upon its oxidation, a competing monovalent guest molecule (blue) favored the formation of monovalent interactions for more efficient

  • Item type:Article
    ID code:45688
    Dates:
    Date
    Event
    14 June 2011
    Published
    17 May 2011
    Published Online
    Subjects:Science > Physics
    Department:Faculty of Science > Physics
    Depositing user: Pure Administrator
    Date deposited:06 Nov 2013 11:23
    Last modified:11 Nov 2024 10:32
    URI:https://strathprints.strath.ac.uk/id/eprint/45688
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