Synthesis of cis,cis-diunsaturated α-meromycolic acid by a palladium-catalysed alkyl–alkyl Negishi reaction

Berretta, Giacomo and Coxon, Geoffrey (2012) Synthesis of cis,cis-diunsaturated α-meromycolic acid by a palladium-catalysed alkyl–alkyl Negishi reaction. Tetrahedron Letters, 53 (2). pp. 214-216. ISSN 0040-4039 (https://doi.org/10.1016/j.tetlet.2011.11.021)

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Abstract

The first total synthesis of cis,cis-diunsaturated α-meromycolic acid has been accomplished using a convergent strategy and a palladium-catalysed alkyl–alkyl Negishi reaction as the key step.