Nucleotide cross-linking induced by photoreactions of novel platinum (IV) azide complexes

Parkinson, J.A. and Muller, P. and Shroder, B. and Kratochwil, N.A. and Coxall, R.A. and Parkin, A. and Parsons, S. and Sadler, P.J. (2003) Nucleotide cross-linking induced by photoreactions of novel platinum (IV) azide complexes. Angewandte Chemie, 42 (3). pp. 335-339. (https://doi.org/10.1002/anie.200390110)

Abstract

Visible light irradiation of inert [PtIV(diam(m)ine)(diazide)] complexes leads to reductive elimination of the azide ligands, production of N2, and formation of bifunctional adducts with guanine bases of the type which are lethal to cancer cells.

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• Item metadata

  Item type:	Article
  ID code:	38590
  Dates:	Date Event 2003 Published
  Subjects:	Science > Chemistry
  Department:	Faculty of Science > Pure and Applied Chemistry
  Depositing user:	Pure Administrator
  Date deposited:	20 Mar 2012 12:22
  Last modified:	08 Apr 2024 16:32
  URI:	https://strathprints.strath.ac.uk/id/eprint/38590