Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis

Milner, Jennifer M and Patel, Amit and Davidson, Rose K and Swingler, Tracey E and Desilets, Antoine and Young, David A and Kelso, Elizabeth B and Donell, Simon T and Cawston, Tim E and Clark, Ian M and Ferrell, William R and Plevin, Robin and Lockhart, John C and Leduc, Richard and Rowan, Andrew D (2010) Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis. Arthritis and Rheumatism, 62 (7). pp. 1955-1966. (https://doi.org/10.1002/art.27476)

Abstract

Increasing evidence implicates serine proteinases in pathologic tissue turnover. The aim of this study was to assess the role of the transmembrane serine proteinase matriptase in cartilage destruction in osteoarthritis (OA).

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• Item metadata

  Item type:	Article
  ID code:	33825
  Dates:	Date Event July 2010 Published
  Subjects:	Medicine > Pharmacy and materia medica Science > Mathematics > Probabilities. Mathematical statistics
  Department:	Faculty of Science > Mathematics and Statistics Faculty of Humanities and Social Sciences (HaSS) > Humanities > English Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Pure Administrator
  Date deposited:	15 Mar 2012 15:18
  Last modified:	08 Apr 2024 19:27
  Related URLs:	Scopus publication
  URI:	https://strathprints.strath.ac.uk/id/eprint/33825