The fat controller : roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review)

Greaves, Jennifer and Prescott, Gerald R and Gorleku, Oforiwa A and Chamberlain, Luke H (2009) The fat controller : roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review). Molecular Membrane Biology, 26 (1). pp. 67-79. (https://doi.org/10.1080/09687680802620351)

Full text not available in this repository.Request a copy

Abstract

The attachment of palmitic acid to the amino acid cysteine via thioester linkage (S-palmitoylation) is a common post-translational modification of eukaryotic proteins. In this review, we discuss the role of palmitoylation as a versatile protein sorting signal, regulating protein trafficking between distinct intracellular compartments and the micro-localization of proteins within membranes.