Toward single-metal-ion sensing by forster resonance energy transfer

Sutter, J.U. and Macmillan, A.M. and Birch, D.J.S. and Rolinski, O.J. (2008) Toward single-metal-ion sensing by forster resonance energy transfer. Annals of the New York Academy of Sciences, 1130. pp. 62-67. ISSN 0077-8923

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Abstract

Here we describe progress toward our objective of detecting single nonfluorescent hydrated metal ions. Single-ion detection represents detection and spectroscopy at the ultimate sensitivity level of approximately 1.6 x 10(-24) M. Achieving this goal would provide a breakthrough in analytical science and allow much more detailed insight into sensor-ion interaction than that available with conventional bulk detection methods. We combine recent advances in confocal microscopy with the sensitivity and the noninvasive nature of fluorescence by analyzing Forster resonance energy transfer between sensor fluorophores and transition metal ions.

ORCID iDs

Sutter, J.U. ORCID logoORCID: https://orcid.org/0000-0002-3782-6338, Macmillan, A.M., Birch, D.J.S. ORCID logoORCID: https://orcid.org/0000-0001-6400-1270 and Rolinski, O.J. ORCID logoORCID: https://orcid.org/0000-0002-7838-779X;
  • Item type:Article
    ID code:17059
    Dates:
    Date
    Event
    2008
    Published
    Notes:Document Type: Proceedings Paper
    Subjects:Science > Physics
    Department:Faculty of Science > Physics
    Depositing user: Strathprints Administrator
    Date deposited:21 Apr 2010 12:00
    Last modified:11 Nov 2024 09:20
    URI:https://strathprints.strath.ac.uk/id/eprint/17059
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