Sex hormones and modulation of immunity against leishmaniasis

Snider, Heidi and Lezama-Davila, Claudio and Alexander, J. and Satoskar, Abhay R. (2009) Sex hormones and modulation of immunity against leishmaniasis. Neuroimmunomodulation, 16 (2). pp. 106-113. ISSN 1021-7401 (http://dx.doi.org/10.1159/000180265)

Abstract

Sex-associated hormones such as estradiol, testosterone and progesterone have all been shown to modulate immune responses, which can result in differential disease outcomes between males and females, as well as between pregnant and nonpregnant females. Most parasitic diseases, including leishmaniasis, usually result in more severe disease in males compared with females. This review highlights our current knowledge concerning the role of sex hormones in modulating leishmaniasis in both clinical settings and experimental disease models.

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• Item metadata

  Item type:	Article
  ID code:	12930
  Dates:	Date Event 2009 Published
  Subjects:	Medicine > Pharmacy and materia medica Science > Microbiology
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Mr Scott Kilgariff
  Date deposited:	21 Aug 2009 15:35
  Last modified:	08 Apr 2024 17:09
  URI:	https://strathprints.strath.ac.uk/id/eprint/12930